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Document Details :
Title: Een 40-jarige man met lage rugpijn
Author(s): BLOCKMANS D, DEGREEF H
Journal: Tijdschrift voor Geneeskunde
Volume: 62 Issue: 5 Date: 2006
A 40-year-old man with low backache
We describe the case of a 40-year-old man known with cutaneous mastocytosis (a mixture of telangiectasia macularis eruptiva perstans and urticaria pigmentosa) who presented with a severe low back pain since 5 months. On standard X-rays and CT-scan of the spine, several vertebral collapses were noted. The assessment of bone mineral density was in the osteoporotic zone (T-score L1-L4: -3.2). Further investigations revealed an increased serum tryptase level. On bone marrow examination, numerous mast cells were seen. This confirmed the diagnosis of systemic mastocytosis, causing osteoporosis.
Osteoporosis in a man of 40 years old is never trivial and an underlying cause (hemochromatosis, multiple myeloma, hypogonadism, steroid excess, systemic mastocytosis,…) should be looked for.