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Document Details :
Title: Een 56-jarige man met thoracale pijn
Author(s): VANSTECHELMAN F, REMELS L
Journal: Tijdschrift voor Geneeskunde
Volume: 66 Issue: 20 Date: 2010
A 56-year-old man with acute chest pain
A 56-year-old patient with chest pain because of an acute non ST elevation myocardial infarct was seen in the emergency room. After initial stabilisation and standard medical approach, our patient was referred for semi-urgent heart catheterisation. Coronary angiogram revealed no coronary stenosis nor occlusions, but a diffuse disturbed wall motion occurred. These findings in combination with patient’s systemic complaints were suggestive that the cardiac damage was caused by a systemic disease or vasculitis.
On cardiac MRI a large zone of subendocardial damage probably due to microvascular obstruction or coronitis caused by vasculitis, did occur.
By further investigations and listing of all symptoms the diagnosis of a Churg-Strauss syndrome was established.
This syndrome is a disease entity characterized by asthma, hypereosinophilia and vasculitis. The disease can be divided into three phases and starts with asthma, allergic rhinitis and nasal polyposis. The second phase is marked by peripheral and tissue eosinophilia associated with pulmonary infiltrates, the third being characterized by systemic vasculitis.
In this article the cardiac and extra-cardiac involvement of the Churg-Strauss syndrome is detailed.