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Document Details :
Title: Renaal angiomyolipoom tijdens de zwangerschap
Author(s): JACOBS A, EERDEKENS C, VERHAMME S, DE SONNAVILLE L, MICHIELS I, VERBOVEN U
Journal: Tijdschrift voor Geneeskunde
Volume: 70 Issue: 17 Date: 2014
Renal angiomyolipomas in pregnancy as a first clinical sign of tuberous sclerosis
A 26-year-old pregnant woman presented with sudden abdominal pain in the right lumbar region, caused by bleeding renal angiomyolipomas, as shown on an MRI. Further investigations and research confirmed the clinical suspicion of tuberous sclerosis (TS).
TS is a rare, genetically inherited disorder. The diagnosis is based on a complete clinical examination of all organs (lungs, heart, kidneys, skin and eyes). mTOR inhibitors (mTOR: “mammalian target of rapamycin”) have recently been approved as a therapeutic option for patients with TS. However, the fetal effect of this treatment requires further clinical research.